Dengue Virus Vaccine Philippines 93%london School of Hygiene & Tropical Medicine (Lshtm)

doi: 10.1080/21645515.2018.1522468. Epub 2018 Oct 12.

Vaccine confidence plummets in the Philippines following dengue vaccine scare: why it matters to pandemic preparedness

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  • PMID: 30309284
  • PMCID: PMC6605722
  • DOI: 10.1080/21645515.2018.1522468

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Vaccine confidence plummets in the Philippines following dengue vaccine scare: why it matters to pandemic preparedness

Heidi J Larson  et al. Hum Vaccin Immunother. 2019 .

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Erratum in

  • Correction.

    [No authors listed] [No authors listed] Hum Vaccin Immunother. 2020 Oct 2;16(10):2577. doi: 10.1080/21645515.2019.1628510. Epub 2019 Jun 18. Hum Vaccin Immunother. 2020. PMID: 31211627 Free PMC article. No abstract available.

Abstract

In November 2017, it was announced that the new dengue vaccine ("Dengvaxia") had risks for those not previously exposed to dengue. While some countries proceeded with adjusting guidance accordingly, the Philippines reacted with outrage and political turmoil with naming and shaming of government officials involved in purchasing the vaccine, as well as scientists involved in the vaccine trials and assessment. The result was broken public trust around the dengue vaccine as well heightened anxiety around vaccines in general. The Vaccine Confidence ProjectTM measured the impact of this crisis, comparing confidence levels in 2015, before the incident, with levels in 2018. The findings reflect a dramatic drop in vaccine confidence from 93% "strongly agreeing" that vaccines are important in 2015 to 32% in 2018. There was a drop in confidence in those strongly agreeing that vaccines are safe from 82% in 2015 to only 21% in 2018; similarly confidence in the effectiveness of vaccines dropped from 82% in 2015 to only 22%. This article highlights the importance of routinely identifying gaps or breakdowns in public confidence in order to rebuild trust, before a pandemic threat, when societal and political cooperation with be key to an effective response.

Keywords: Dengvaxia; Philippines; Vaccine confidence; dengue vaccine; pandemic preparedness; public trust; risk perception; vaccine confidence index.

Figures

Figure 1.
Figure 1.

Confidence in vaccines has declined substantially in the Philippines between 2015 and 2018. Vaccine confidence in the Philippines has declined across all four measures of confidence measured by the Vaccine Confidence ProjectTM: the percentage of respondents agreeing that vaccines are important for children to have has decreased from 99.5% in 2015 to 76.2% in 2018. Similar drops are observed for vaccine safety (97.3% to 65.2%), effectiveness (97.0% to 67.9%), and compatibility with religious beliefs (83.8% to 67.9%).

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Dengue Virus Vaccine Philippines 93%london School of Hygiene & Tropical Medicine (Lshtm)

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